Borzoi heart study

The Texas A&M College of Veterinary Medicine & Biomedical Sciences is seeking participants for its study on heart disease in the Borzoi breed:

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Genetics of Inherited Heart Disease in the Borzoi and other sighthound breeds

Recent research in Borzoi dogs has revealed that the breed may experience sudden, unexplained death. About 85% of sudden, unexplained deaths in humans are linked to an underlying heart disease. Our existing research in Borzoi dogs has shown that they are predisposed to developing arrhythmias (abnormal heart rhythms) and dilated cardiomyopathy (a heart muscle disease causing dilated heart chambers and weak pumping function). Our study aims to identify genetic mutations associated with heart disease in Borzoi dogs and document their existence in other sighthound breeds.

Eligibility

Any sighthound, age and sex, and all vet records must be provided. OFA and Holter forms if able.

What Happens

We will collect saliva samples from both healthy sighthound breeds and sighthound breeds affected by arrhythmias and/or dilated cardiomyopathy.

We will extract DNA from these samples and perform genomic sequencing on a select number while retaining the remainder for further screening.

By analyzing the sequencing data, we can compare the genes of healthy and affected dogs and identify variants linked to their heart conditions.

We will also compare the findings in Borzoi dogs to results from other sighthound breeds.

No genetic results will be available to study participants, though they may read the paper upon publication.

Financial Incentives/Obligations

No direct compensation is provided for participation. We will send the kit for free, we only ask for the owner to pay for return shipping.

If interested, please sign up on our Study Page link and register each dog separately: https://studypages.com/s/genetics-of-inherited-heart-disease-in-borzoi-dogs-and-other-sighthound-breeds-815394/

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Disclaimer

The Breed Archive is not affiliated with this study or The Texas A&M College of Veterinary Medicine & Biomedical Sciences but supports their cause.